DISCOVERY OF BIS-IMIDAZOLINE DERIVATIVES AS NEW CXCR4 LIGANDS

Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands

The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers.Here, we HEMP PRO FIBRE identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-throughput screening assay.These are bis-im

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Designing Automatic Guided Device of Books

There are several methods returning scattered books in library, such as asking visitors to put them back to the bookshelf, recruiting more employees, or creating system that can return the books automatically.But, by using the system, visitors no need to walk to certain bookshelf.The system itself called Automatic Guided Device included of Automati

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Improvement of diaphragmatic excursion in the supine position in a patient with idiopathic pleuroparenchymal fibroelastosis: A case report

Idiopathic pleuroparenchymal fibroelastosis (iPPFE) is a rare form of idiopathic interstitial pneumonia.We report a case of a patient with iPPFE in whom postural changes improved diaphragmatic excursion (DE) and exercise tolerance.Chest radiography showed a greater elevation of the diaphragm at maximum Other Digestive Support Products expiration in

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